Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
| ▸ | GRK5 | P34947 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | MST1R | Q04912 | 1/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655135 | 0.88 | QPCT (0.37) | KDM4EALDH1A1MAPTTDP1NPC1 | |
| SCHEMBL9658073 | 0.81 | MAPT (0.43) | KDM4EALDH1A1MAPTTDP1NPC1 | |
| SCHEMBL11175719 | 0.78 | BAZ2B (0.37) | KDM4EALDH1A1MAPTTDP1NPC1 | |
| SCHEMBL25045782 | 0.73 | KDM4E (0.38) | KDM4EALDH1A1CHEK1MAPTLIMK1 | |
| SCHEMBL23104811 | 0.73 | LCK (0.38) | KDM4EALDH1A1CHEK1MAPTLIMK1 | |
| SCHEMBL9730543 | 0.72 | RET (0.35) | KDM4EALDH1A1CHEK1MAPTLIMK1 | |
| SCHEMBL24127754 | 0.70 | SSTR4 (0.42) | KDM4EALDH1A1MAPTRAB9AHPGD | |
| SCHEMBL23707124 | 0.70 | TP53 (0.39) | KDM4EALDH1A1MAPTGLAGAA | |
| SCHEMBL23132917 | 0.70 | NR1I2 (0.33) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL11177746 | 0.70 | ATP4A (0.54) | MAPTMAPK14TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171858-A | Preparation of certain 5,6-dihydro-8-phenyl-imidazo[1,5-a]pyridines | SCHERING A.G. (DE) | 1992-12-15 | — | — | US | disclosed |
| US-5171859-A | Certain 2-aminomethyl-3-phenyl-pyridine intermediates for certain 8-phenyl-imidazo[1,5-a]pyridines | SCHERING A.G. (DE) | 1992-12-15 | — | — | US | disclosed |
| US-5026712-A | Novel imidazo[1,5-a]pyridines, useful as cardiovascular and CNS agents | SCHERING AG (DE) | 1991-06-25 | — | — | US | disclosed |