Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | LTK | P29376 | 1/20 | 0.35 |
| ▸ | GRK5 | P34947 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | MST1R | Q04912 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655128 | 0.72 | KDM4E (0.42) | RETMETLTKGRK5CDK8 | |
| SCHEMBL11212892 | 0.64 | ADRB2 (0.39) | L3MBTL1ALDH1A1KDM4EKMT2AADRB2 | |
| SCHEMBL170787 | 0.63 | DPP4 (0.54) | RETMETLTKCDK8LRRK2 | |
| SCHEMBL28758160 | 0.62 | DPP4 (0.52) | RETMETLTKCDK8LRRK2 | |
| SCHEMBL27684898 | 0.62 | DPP4 (0.52) | RETMETLTKCDK8LRRK2 | |
| Water SCHEMBL821345 | 0.62 | DPP4 (0.52) | RETMETLTKCDK8LRRK2 | |
| Biphenyl SCHEMBL7928631 | 0.62 | DPP4 (0.52) | RETMETLTKCDK8LRRK2 | |
| SCHEMBL27886719 | 0.62 | GABRA1 (0.47) | RETMETLTKCDK8LRRK2 | |
| SCHEMBL3125568 | 0.61 | GABRA1 (0.50) | RETMETLTKCDK8LRRK2 | |
| SCHEMBL4078175 | 0.61 | KDM4E (0.65) | ALDH1A1KDM4EMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171859-A | Certain 2-aminomethyl-3-phenyl-pyridine intermediates for certain 8-phenyl-imidazo[1,5-a]pyridines | SCHERING A.G. (DE) | 1992-12-15 | — | — | US | disclosed |