Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658643 | 0.88 | HSPB1 (0.58) | HSPB1TDP1ATMTTRHTT | |
| SCHEMBL9656755 | 0.87 | HSPB1 (0.56) | HSPB1TDP1ATML3MBTL1TTR | |
| SCHEMBL9655274 | 0.87 | HSPB1 (0.56) | HSPB1TDP1ATML3MBTL1MAPT | |
| SCHEMBL31522185 | 0.85 | HSPB1 (0.70) | HSPB1TDP1ATML3MBTL1MAPT | |
| SCHEMBL9658575 | 0.84 | HSPB1 (0.54) | HSPB1TDP1ATMTTRMAPT | |
| SCHEMBL9656834 | 0.84 | L3MBTL1 (0.55) | HSPB1TDP1ATML3MBTL1MAPT | |
| SCHEMBL9657490 | 0.84 | HSPB1 (0.53) | HSPB1TDP1ATML3MBTL1TTR | |
| SCHEMBL9655201 | 0.84 | HSPB1 (0.53) | HSPB1TDP1ATML3MBTL1TTR | |
| SCHEMBL9655263 | 0.82 | HSPB1 (0.51) | HSPB1TDP1ATMMAPTGAA | |
| SCHEMBL9655176 | 0.82 | HSPB1 (0.51) | HSPB1TDP1ATML3MBTL1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273369-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-04 | — | — | EP | disclosed |
| US-4866091-A | ANTINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0273369-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-06 | — | — | EP | disclosed |