Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 11/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.40 |
| ▸ | MEN1 | O00255 | 9/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655211 | 1.00 | ACHE (0.43) | ACHEHSD17B10MAPTKMT2AMEN1 | |
| SCHEMBL9655498 | 0.81 | HTT (0.38) | HSD17B10MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9655492 | 0.81 | HTT (0.38) | HSD17B10MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL19815804 | 0.81 | ACHE (0.51) | ACHEHSD17B10MAPTKMT2AMEN1 | |
| SCHEMBL21046020 | 0.81 | ACHE (0.51) | ACHEHSD17B10MAPTKMT2AMEN1 | |
| SCHEMBL9655433 | 0.79 | ALDH1A1 (0.43) | ACHEMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9655439 | 0.79 | ALDH1A1 (0.43) | ACHEMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9652847 | 0.76 | MEN1 (0.42) | MAPTKMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL9652853 | 0.76 | MEN1 (0.42) | MAPTKMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL5026213 | 0.72 | ACHE (0.75) | ACHEHSD17B10MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5099016-A | Mitomycin analogs containing 7-alkoxy groups and disulfides as antibiotics | BRISTOL-MYERS COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-5097036-A | Mitomycin analogs; antibiotics antitumor agents | BRISTOL-MYERS COMPANY (US) | 1992-03-17 | — | — | US | disclosed |
| US-4927943-A | ANTITUMOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1990-05-22 | — | — | US | disclosed |
| US-4814445-A | ETHERIFICATION, ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1989-03-21 | — | — | US | disclosed |