Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655282 | 1.00 | RAB9A (0.65) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL9656096 | 0.80 | RAB9A (0.76) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL9656092 | 0.80 | RAB9A (0.76) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL27596097 | 0.79 | CTSL (0.68) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL2777077 | 0.75 | NPC1 (0.48) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL2777080 | 0.75 | NPC1 (0.48) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL9656950 | 0.74 | NPC1 (0.47) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL720916 | 0.74 | TP53 (0.68) | RAB9ASMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL9768607 | 0.72 | TP53 (0.53) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL9768608 | 0.72 | TP53 (0.53) | RAB9ASMN1; SMN2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299974-B1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-01-22 | — | — | EP | claimed |
| EP-0299974-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS. | UPJOHN CO (US) | 1989-01-25 | — | — | EP | claimed |
| WO-1987006127-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-10-22 | — | — | WO | claimed |