Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655667 | 0.87 | KMT2A (0.48) | CYP3A4CYP1A2ALOX5KMT2AMEN1 | |
| SCHEMBL9313724 | 0.85 | CYP3A4 (0.47) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL9655147 | 0.85 | PSEN1 (0.49) | CYP3A4CYP1A2KMT2AMEN1MAPK1 | |
| SCHEMBL9313627 | 0.85 | MEN1 (0.39) | CYP3A4CYP1A2ALOX5LMNAKMT2A | |
| SCHEMBL9314952 | 0.85 | PSEN1 (0.38) | CYP3A4CYP1A2MAPTKMT2ATDP1 | |
| SCHEMBL9428539 | 0.83 | USP2 (0.46) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL9427829 | 0.83 | PTGS1 (0.56) | CYP3A4TSHRPTGS1PTGS2CYP1A2 | |
| SCHEMBL9313487 | 0.83 | PSEN1 (0.40) | CYP3A4CYP1A2LMNAKMT2AMEN1 | |
| SCHEMBL9314041 | 0.83 | PSEN1 (0.42) | CYP3A4CYP1A2KMT2AMEN1MAPK1 | |
| SCHEMBL9313502 | 0.82 | BCHE (0.52) | CYP3A4TSHRPTGS1PTGS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512899-A1 | Benzopyran compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-11-11 | — | — | EP | disclosed |