Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 10/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313487 | 0.91 | PSEN1 (0.40) | PSEN1MAPK1CYP1A2CYP3A4MEN1 | |
| SCHEMBL9314952 | 0.89 | PSEN1 (0.38) | PSEN1MAPK1CYP1A2CYP3A4MEN1 | |
| SCHEMBL9312778 | 0.87 | PSEN1 (0.51) | PSEN1PTPN1GSTO1MEN1KMT2A | |
| SCHEMBL9655667 | 0.87 | KMT2A (0.48) | PSEN1MAPK1CYP1A2CYP3A4PTPN1 | |
| SCHEMBL9314041 | 0.87 | PSEN1 (0.42) | PSEN1MAPK1CYP1A2CYP3A4MEN1 | |
| SCHEMBL9313627 | 0.86 | MEN1 (0.39) | PSEN1MAPK1CYP1A2CYP3A4PTPN1 | |
| SCHEMBL9313801 | 0.86 | PSEN1 (0.54) | PSEN1PTPN1GSTO1MEN1KMT2A | |
| SCHEMBL9312779 | 0.85 | PSEN1 (0.52) | PSEN1MAPK1CYP1A2CYP3A4 | |
| SCHEMBL9655394 | 0.85 | CYP3A4 (0.44) | MAPK1CYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL9255031 | 0.84 | PSEN1 (0.50) | PSEN1MAPK1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512899-A1 | Benzopyran compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-11-11 | — | — | EP | disclosed |