Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655634 | 0.94 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9658801 | 0.92 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9701759 | 0.87 | AGTR2 (0.59) | AGTR1AGTR2 | |
| SCHEMBL9657140 | 0.86 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9657724 | 0.86 | AGTR2 (0.45) | AGTR1AGTR2 | |
| SCHEMBL7384188 | 0.85 | AGTR2 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9702515 | 0.83 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL7392767 | 0.83 | AGTR2 (0.43) | AGTR1AGTR2 | |
| SCHEMBL7379235 | 0.83 | AGTR2 (0.56) | AGTR1AGTR2 | |
| SCHEMBL7941438 | 0.81 | AGTR1 (0.56) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510813-A1 | Angiotensin II antagonists incorporating a nitrogen containing six membered ring heterocycle | MERCK & CO. INC. (US) | 1992-10-28 | — | — | EP | disclosed |
| US-5128327-A | Hypotensive agents; congestive heart failure; antidepressants; anxiolytic agents; cognition activators | MERCK & CO., INC. (US) | 1992-07-07 | — | — | US | disclosed |