SCHEMBL9655858

SCHEMBL9655858

O=C(Nc1ccccc1)c1snc(Cl)c1Cl

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.51
LMNA P02545 3/20 0.51
POLB P06746 3/20 0.50
RAB9A P51151 7/20 0.48
RECQL P46063 1/20 0.48
NPC1 O15118 6/20 0.47
MAPT P10636 5/20 0.47
HTT P42858 4/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
KDM4E B2RXH2 2/20 0.44
HPGD P15428 1/20 0.43
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3571411 0.87 RAB9A (0.54) LMNAPOLBRAB9ANPC1MAPT
SCHEMBL13439612 0.84 RAB9A (0.61) ALDH1A1LMNAPOLBRAB9ANPC1
SCHEMBL28540549 0.82 SMN1; SMN2 (0.54) ALDH1A1LMNAPOLBRAB9ANPC1
SCHEMBL13406697 0.81 RAB9A (0.55) LMNARAB9ANPC1MAPTSMN1; SMN2
SCHEMBL23810081 0.81 ALDH1A1 (0.37) ALDH1A1LMNAPOLBRAB9ARECQL
SCHEMBL23810105 0.81 ALDH1A1 (0.40) ALDH1A1LMNAPOLBRAB9ARECQL
SCHEMBL9656149 0.79 NPC1 (0.55) RAB9ANPC1SMN1; SMN2KDM4E
SCHEMBL17342166 0.79 HTT (0.54) ALDH1A1LMNAPOLBRAB9ANPC1
SCHEMBL13406694 0.78 RAB9A (0.48) ALDH1A1LMNAPOLBRAB9ANPC1
SCHEMBL28546063 0.78 POLB (0.46) ALDH1A1POLBRAB9ANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5141552-A Applying isothiazole plant growth regulator to one variety, pollinating with another UNIVERSITY PATENTS, INC. (US) 1992-08-25 US disclosed
EP-0302183-A2 Hybrid corn seed and method CHEMBRED, INC. (US) 1989-02-08 EP disclosed