Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 12/20 | 0.60 |
| ▸ | CYSLTR2 | Q9NS75 | 9/20 | 0.60 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9654592 | 0.91 | ALOX5 (0.60) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL14021858 | 0.86 | CYSLTR1 (0.72) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL3362235 | 0.83 | CYSLTR1 (0.63) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9865792 | 0.82 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL14021552 | 0.82 | CYSLTR1 (0.74) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL14021592 | 0.81 | CYSLTR1 (0.87) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9656045 | 0.78 | CYSLTR1 (0.85) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL9508040 | 0.77 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL9876648 | 0.77 | CYSLTR2 (0.60) | CYSLTR1CYSLTR2GPBAR1ALOX5 | |
| SCHEMBL9303005 | 0.76 | CYSLTR1 (0.48) | CYSLTR1CYSLTR2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309541-B1 | SULFONYLCARBOXAMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-01-02 | — | — | EP | claimed |
| EP-0309541-A4 | SULFONYLCARBOXAMIDES. | AMERICAN HOME PROD (US) | 1989-07-24 | — | — | EP | claimed |
| EP-0309541-A1 | SULFONYLCARBOXAMIDES. | AMERICAN HOME PROD (US) | 1989-04-05 | — | — | EP | claimed |
| WO-1988006886-A1 | SULFONYLCARBOXAMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-09-22 | — | — | WO | claimed |
| EP-0309541-B1 | SULFONYLCARBOXAMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-01-02 | — | — | EP | disclosed |