Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729214 | 0.80 | MC4R (0.42) | ACP3MAPK1CNR2POLBTDP1 | |
| SCHEMBL1728842 | 0.80 | MC4R (0.42) | ACP3MAPK1CNR2POLBTDP1 | |
| SCHEMBL12261511 | 0.80 | MC4R (0.42) | ACP3MAPK1CNR2POLBTDP1 | |
| SCHEMBL28565247 | 0.79 | PDE2A (0.49) | ACP3MAPK1CNR2POLBMC4R | |
| Hydrochloric Acid SCHEMBL4512926 | 0.77 | CNR2 (0.44) | ACP3MAPK1CNR2POLBTSHR | |
| SCHEMBL8539373 | 0.77 | ACP3 (0.49) | ACP3CNR2MC4RHSD11B1P2RX7 | |
| SCHEMBL9203944 | 0.77 | KDM4E (0.43) | ACP3MAPK1KDM4ETDP1TSHR | |
| SCHEMBL1727762 | 0.76 | P2RX7 (0.47) | ACP3CNR2POLBTDP1MC4R | |
| SCHEMBL334979 | 0.76 | P2RX7 (0.47) | ACP3CNR2POLBTDP1MC4R | |
| SCHEMBL1258401 | 0.76 | P2RX7 (0.47) | ACP3CNR2POLBTDP1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5099067-A | Use of ammonium formate as a hydrogen transfer reagent for reduction of chiral nitro compounds with retention of configuration | NORTHWESTERN UNIVERSITY (US) | 1992-03-24 | — | — | US | disclosed |