Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2208288 | 0.85 | ACP3 (0.41) | ACP3CNR2POLBMAPK1MC4R | |
| SCHEMBL8760976 | 0.82 | LMNA (0.47) | PDE2ALMNATSHRCYP1A2CYP3A4 | |
| SCHEMBL163013 | 0.82 | PNMT (0.47) | ACP3CNR2POLBP2RX7CYP3A4 | |
| SCHEMBL5698922 | 0.82 | ACP3 (0.45) | LMNAACP3CNR2MC4RP2RX7 | |
| SCHEMBL7148448 | 0.82 | PNMT (0.47) | ACP3CNR2POLBP2RX7CYP3A4 | |
| SCHEMBL6055159 | 0.82 | LMNA (0.47) | PDE2ALMNAPOLBTSHRCYP1A2 | |
| SCHEMBL4103038 | 0.82 | PDE2A (0.44) | PDE2ALMNAPOLBMAPK1P2RX7 | |
| SCHEMBL13168657 | 0.82 | ACP3 (0.47) | PDE2ALMNAACP3CNR2MC4R | |
| SCHEMBL29907993 | 0.82 | ACP3 (0.47) | PDE2ALMNAACP3CNR2MC4R | |
| SCHEMBL29580255 | 0.82 | ACP3 (0.47) | PDE2ALMNAACP3CNR2MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112830879-A | Preparation method of cinacalcet hydrochloride | 北京泰德制药股份有限公司 | 2021-05-25 | — | — | CN | disclosed |