Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.61 |
| ▸ | PGR | P06401 | 4/20 | 0.57 |
| ▸ | AR | P10275 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656240 | 1.00 | NR3C1 (0.61) | NR3C1PGRARHSD17B10LMNA | |
| SCHEMBL11141463 | 0.91 | NR3C1 (0.59) | NR3C1PGRARHSD17B10LMNA | |
| SCHEMBL11138448 | 0.91 | NR3C1 (0.59) | NR3C1PGRARHSD17B10LMNA | |
| SCHEMBL11526150 | 0.91 | NR3C1 (0.59) | NR3C1PGRARHSD17B10LMNA | |
| SCHEMBL11138455 | 0.91 | NR3C1 (0.59) | NR3C1PGRARHSD17B10LMNA | |
| SCHEMBL11688398 | 0.89 | NR3C1 (0.60) | NR3C1PGRARHSD17B10LMNA | |
| SCHEMBL11688405 | 0.89 | NR3C1 (0.60) | NR3C1PGRARHSD17B10LMNA | |
| SCHEMBL11688389 | 0.89 | NR3C1 (0.60) | NR3C1PGRARHSD17B10LMNA | |
| SCHEMBL11523625 | 0.88 | NR3C1 (0.64) | NR3C1PGRARHSD17B10LMNA | |
| SCHEMBL11523629 | 0.88 | NR3C1 (0.64) | NR3C1PGRARHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127216-B1 | PROCESS FOR THE PREPARATION OF 21-HYDROXY-20-KETO-DELTA16-STEROIDS AND INTERMEDIATE COMPOUNDS FORMED IN THIS PROCESS | ROUSSEL-UCLAF (FR) | 1992-01-02 | — | — | EP | disclosed |
| EP-0123736-A1 | New process for the preparation of 21-hydroxy-20-keto-delta 16-steroids and new intermediate compounds formed in this process | GIST-BROCADES N.V. (NL) | 1984-11-07 | — | — | EP | disclosed |