Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.64 |
| ▸ | PGR | P06401 | 4/20 | 0.64 |
| ▸ | HRH1 | P35367 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | AR | P10275 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11523625 | 1.00 | NR3C1 (0.64) | NR3C1HIF1APGRHRH1LMNA | |
| SCHEMBL11523621 | 1.00 | NR3C1 (0.64) | NR3C1HIF1APGRHRH1LMNA | |
| SCHEMBL11688880 | 0.92 | LMNA (0.61) | NR3C1HIF1APGRHRH1LMNA | |
| SCHEMBL11688872 | 0.92 | LMNA (0.61) | NR3C1HIF1APGRHRH1LMNA | |
| SCHEMBL11688884 | 0.92 | LMNA (0.61) | NR3C1HIF1APGRHRH1LMNA | |
| SCHEMBL9656247 | 0.88 | NR3C1 (0.61) | NR3C1HIF1APGRHRH1LMNA | |
| SCHEMBL9656240 | 0.88 | NR3C1 (0.61) | NR3C1HIF1APGRHRH1LMNA | |
| SCHEMBL11138455 | 0.87 | NR3C1 (0.59) | NR3C1HIF1APGRHRH1LMNA | |
| SCHEMBL11138448 | 0.87 | NR3C1 (0.59) | NR3C1HIF1APGRHRH1LMNA | |
| SCHEMBL11141463 | 0.87 | NR3C1 (0.59) | NR3C1HIF1APGRHRH1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4155917-A | WITH OZONE AND AN ALKANOL | E. R. SQUIBB & SONS, INC. (US) | 1979-05-22 | — | — | US | disclosed |
| EP-0000546-A1 | D-homo oxasteroids, processes for their preparation, their use in preparing pharmaceutical compositions with antiinflammatocy activity and pharmaceutical compositions containing them | E.R. Squibb & Sons, Inc. (US) | 1979-02-07 | — | — | EP | disclosed |
| US-4116978-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1978-09-26 | — | — | US | disclosed |
| US-3937720-A | ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1976-02-10 | — | — | US | disclosed |