SCHEMBL9656602

SCHEMBL9656602

CCCCCCNC(=O)Oc1c(Oc2ccccc2)c(Oc2ccccc2)c(OC(=O)NCCCCCC)c2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.53
ZDHHC2 Q9UIJ5 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9656418 0.95 NCEH1 (0.52) MGLL
SCHEMBL9657823 0.89 MAPT (0.45)
SCHEMBL9656447 0.86 NCEH1 (0.47) ZDHHC2
SCHEMBL9656357 0.85 MGLL (0.54) MGLL
SCHEMBL9656370 0.84 MGLL (0.52) MGLL
SCHEMBL9263670 0.84 MGLL (0.70) MGLLZDHHC2
SCHEMBL9268320 0.84 MGLL (0.70) MGLLZDHHC2
SCHEMBL22472046 0.83 MGLL (0.73) MGLLZDHHC2
SCHEMBL21891896 0.83 MGLL (0.73) MGLLZDHHC2
SCHEMBL6757093 0.83 MGLL (0.73) MGLLZDHHC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5134161-A Enzyme inhibitors for skin disorders, antiinflammatory agents SYNTEX (U.S.A.) INC. (US) 1992-07-28 US disclosed
US-4786652-A TOPICAL ADMINISTRATION SYNTEX (U.S.A.) INC. (US) 1988-11-22 US disclosed
EP-0282006-A1 Naphtalene anti-psoriatic agents SYNTEX (U.S.A.) INC. (US) 1988-09-14 EP disclosed