Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656780 | 0.94 | NCEH1 (0.55) | MGLLHTTNCEH1 | |
| SCHEMBL9656406 | 0.88 | KDM4E (0.46) | EPHX1ALDH1A1NCEH1 | |
| SCHEMBL9656370 | 0.88 | MGLL (0.52) | MGLLNCEH1 | |
| SCHEMBL9656373 | 0.86 | MGLL (0.51) | MGLLEPHX1ALDH1A1HTTNCEH1 | |
| SCHEMBL9659558 | 0.86 | MGLL (0.56) | MGLL | |
| SCHEMBL9656602 | 0.85 | MGLL (0.53) | MGLL | |
| SCHEMBL9656588 | 0.85 | ABCB11 (0.56) | MGLL | |
| SCHEMBL9659203 | 0.85 | MGLL (0.58) | MGLLNCEH1 | |
| SCHEMBL9656335 | 0.85 | MGLL (0.58) | MGLLNCEH1 | |
| SCHEMBL9657711 | 0.82 | KDM4E (0.49) | ALDH1A1NCEH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |