SCHEMBL9656743

SCHEMBL9656743

CC(CCc1nc(N)c2[nH]cnc2n1)=[N+](C)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.45
GDA Q9Y2T3 1/20 0.45
POLA1 P09884 2/20 0.38
CDK2 P24941 7/20 0.38
CDK1 P06493 6/20 0.38
CCNB1 P14635 6/20 0.38
CCNA2 P20248 6/20 0.38
CCNA1 P78396 6/20 0.38
MGMT P16455 4/20 0.38
PI4KA P42356 2/20 0.36
PI4K2B Q8TCG2 2/20 0.36
PI4K2A Q9BTU6 2/20 0.36
PI4KB Q9UBF8 2/20 0.36
LMNA P02545 1/20 0.36
DRD3 P35462 1/20 0.36
XDH P47989 1/20 0.36
LRRK2 Q5S007 1/20 0.36
KDR P35968 1/20 0.36
AURKB Q96GD4 1/20 0.36
MAP3K5 Q99683 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9656461 0.86 PDPK1 (0.47) PDPK1GDAPOLA1CDK2CDK1
SCHEMBL29677204 0.82 CDK2 (0.49) PDPK1GDAPOLA1CDK2CDK1
SCHEMBL136630 0.82 CDK2 (0.49) PDPK1GDAPOLA1CDK2CDK1
SCHEMBL9656473 0.80 PDPK1 (0.46) PDPK1GDAPOLA1CDK2CDK1
SCHEMBL11222102 0.80 PDPK1 (0.63) PDPK1GDAPOLA1CDK2CDK1
SCHEMBL215054 0.77 PDPK1 (0.56) PDPK1GDAPOLA1CDK2CDK1
SCHEMBL29620672 0.77 PDPK1 (0.56) PDPK1GDAPOLA1CDK2CDK1
SCHEMBL6267288 0.77 PDPK1 (0.56) PDPK1GDAPOLA1CDK2CDK1
SCHEMBL29514836 0.77 PDPK1 (0.56) PDPK1GDAPOLA1CDK2CDK1
Phosphoric Acid SCHEMBL214567 0.77 MGMT (0.44) PDPK1GDAPOLA1CDK2CDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0508777-A2 Novel adenine derivatives and their use as plant growth regulators MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-10-14 EP disclosed