Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 7/20 | 0.47 |
| ▸ | CCR2 | P41597 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29748830 | 0.91 | PTGS2 (0.55) | PTGS2BRD4CCR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL441676 | 0.91 | PTGS2 (0.55) | PTGS2BRD4CCR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9655142 | 0.84 | PTGS2 (0.55) | PTGS2BRD4CCR2ALDH1A1MAPT | |
| SCHEMBL10416533 | 0.83 | PTGS2 (0.59) | PTGS2BRD4CCR2ALDH1A1EP300 | |
| SCHEMBL10415449 | 0.82 | PTGS2 (0.55) | PTGS2BRD4CCR2ALDH1A1MAPT | |
| SCHEMBL9656728 | 0.82 | PTGS2 (0.53) | PTGS2BRD4CCR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9657518 | 0.81 | PTGS2 (0.55) | PTGS2BRD4CCR2ALDH1A1CYP1A2 | |
| SCHEMBL8524487 | 0.81 | PTGS2 (0.59) | PTGS2BRD4CCR2MAPTEP300 | |
| SCHEMBL9656981 | 0.81 | PTGS2 (0.54) | PTGS2BRD4CCR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9656825 | 0.81 | PTGS2 (0.54) | PTGS2BRD4CCR2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273369-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-04 | — | — | EP | disclosed |
| US-4866091-A | ANTINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |