Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.62 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | SHBG | P04278 | 3/20 | 0.62 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.62 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.62 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | THPO | P40225 | 1/20 | 0.62 |
| ▸ | MTOR | P42345 | 1/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655893 | 1.00 | HIF1A (0.62) | HIF1ANR3C2SMN1; SMN2HSD17B10SHBG | |
| SCHEMBL9655906 | 1.00 | HIF1A (0.62) | HIF1ANR3C2SMN1; SMN2HSD17B10SHBG | |
| SCHEMBL10599706 | 0.88 | HIF1A (0.64) | HIF1ANR3C2SMN1; SMN2HSD17B10SHBG | |
| SCHEMBL10599694 | 0.88 | HIF1A (0.64) | HIF1ANR3C2SMN1; SMN2HSD17B10SHBG | |
| SCHEMBL9653514 | 0.84 | CYP17A1 (0.78) | HIF1ANR3C2SMN1; SMN2HSD17B10SHBG | |
| SCHEMBL14935584 | 0.84 | HIF1A (0.64) | HIF1ANR3C2SMN1; SMN2HSD17B10SHBG | |
| SCHEMBL9687624 | 0.83 | HIF1A (0.52) | HIF1ANR3C2SMN1; SMN2HSD17B10SHBG | |
| SCHEMBL9687638 | 0.83 | HIF1A (0.52) | HIF1ANR3C2SMN1; SMN2HSD17B10SHBG | |
| SCHEMBL24862085 | 0.81 | NR3C1 (0.59) | HIF1ANR3C2SMN1; SMN2HSD17B10SERPINA6 | |
| SCHEMBL9504455 | 0.81 | NR3C1 (0.59) | HIF1ANR3C2SMN1; SMN2HSD17B10SERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127216-B1 | PROCESS FOR THE PREPARATION OF 21-HYDROXY-20-KETO-DELTA16-STEROIDS AND INTERMEDIATE COMPOUNDS FORMED IN THIS PROCESS | ROUSSEL-UCLAF (FR) | 1992-01-02 | — | — | EP | disclosed |
| EP-0127216-A1 | Process for the preparation of 21-hydroxy-20-keto-delta16-steroids and intermediate compounds formed in this process | ROUSSEL-UCLAF (FR) | 1984-12-05 | — | — | EP | disclosed |