Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656425 | 0.92 | ABCB11 (0.50) | ABCB11SMN1; SMN2MAPTTAS1R3TAS1R1 | |
| SCHEMBL9654917 | 0.86 | ABCB11 (0.50) | ABCB11SMN1; SMN2MAPTTAS1R3TAS1R1 | |
| SCHEMBL9657798 | 0.86 | ABCB11 (0.59) | ABCB11SMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL9654673 | 0.86 | ABCB11 (0.59) | ABCB11SMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL9627563 | 0.83 | ABCB11 (0.63) | ABCB11MAPTMAOBKDM4EPOLB | |
| SCHEMBL9627670 | 0.83 | ABCB11 (0.59) | ABCB11MAPTMAOBKDM4EPOLB | |
| SCHEMBL9656448 | 0.80 | ABCB11 (0.70) | ABCB11SMN1; SMN2MAPTKDM4EGAA | |
| SCHEMBL9654842 | 0.79 | ABCB11 (0.47) | ABCB11SMN1; SMN2POLBTSHRALOX15 | |
| SCHEMBL9660000 | 0.78 | ABCB11 (0.44) | ABCB11SMN1; SMN2MAPTPOLBGAA | |
| SCHEMBL9658326 | 0.78 | ABCB11 (0.55) | ABCB11SMN1; SMN2MAPTTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |