Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 20/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703532 | 0.87 | AGTR1 (0.52) | AGTR1 | |
| SCHEMBL9655664 | 0.84 | AGTR1 (0.54) | AGTR1 | |
| SCHEMBL3640446 | 0.77 | AGTR1 (0.62) | AGTR1 | |
| SCHEMBL9657098 | 0.73 | AGTR1 (0.43) | AGTR1 | |
| SCHEMBL9657763 | 0.72 | AGTR2 (0.47) | AGTR1 | |
| SCHEMBL9657168 | 0.72 | AGTR1 (0.45) | AGTR1 | |
| SCHEMBL9655735 | 0.71 | AGTR2 (0.57) | AGTR1 | |
| SCHEMBL3636583 | 0.70 | AGTR1 (0.59) | AGTR1 | |
| SCHEMBL9872247 | 0.70 | AGTR1 (0.37) | AGTR1 | |
| Ammonia Solution, Strong SCHEMBL8971516 | 0.69 | AGTR1 (0.51) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128327-A | Hypotensive agents; congestive heart failure; antidepressants; anxiolytic agents; cognition activators | MERCK & CO., INC. (US) | 1992-07-07 | — | — | US | disclosed |