Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627627 | 0.84 | MAPT (0.48) | TSHRHPGDMGAMMEN1KMT2A | |
| SCHEMBL9628108 | 0.83 | ABCB11 (0.46) | TSHRHPGDMGAMMEN1KMT2A | |
| SCHEMBL9654846 | 0.82 | CSNK2A2 (0.43) | HPGDMEN1KMT2AMAPTTP53 | |
| SCHEMBL9657986 | 0.81 | HIF1A (0.44) | HPGDMGAMMEN1KMT2AMAPT | |
| SCHEMBL9657787 | 0.81 | HPGD (0.44) | TSHRHPGDMEN1KMT2AMAPT | |
| SCHEMBL9656717 | 0.81 | PPM1A (0.40) | HPGDMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL9627602 | 0.80 | ABCB11 (0.46) | TSHRHPGDMGAMMEN1KMT2A | |
| SCHEMBL29700360 | 0.80 | LMNA (0.50) | HPGDMEN1KMT2AMAPTTP53 | |
| SCHEMBL9657859 | 0.80 | LMNA (0.50) | HPGDMEN1KMT2AMAPTTP53 | |
| SCHEMBL9627901 | 0.79 | ABCB11 (0.55) | TSHRHPGDMGAMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |