Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 10/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21896497 | 0.88 | POLB (0.55) | ACACBPOLBLMNATBXAS1NPC1 | |
| SCHEMBL9519327 | 0.82 | PTAFR (0.60) | LMNA | |
| SCHEMBL9519330 | 0.82 | PTAFR (0.60) | LMNA | |
| SCHEMBL30801050 | 0.82 | GPR132 (0.55) | ACACBLMNATBXAS1FDPS | |
| SCHEMBL3781118 | 0.82 | GPR132 (0.55) | ACACBLMNATBXAS1FDPS | |
| SCHEMBL3781113 | 0.82 | GPR132 (0.55) | ACACBLMNATBXAS1FDPS | |
| SCHEMBL6192467 | 0.82 | ACACB (0.48) | ACACBTBXAS1FDPS | |
| SCHEMBL7862745 | 0.82 | ACACB (0.50) | ACACBPOLBLMNATBXAS1FDPS | |
| SCHEMBL6192282 | 0.82 | GPR132 (0.55) | ACACBLMNATBXAS1FDPS | |
| SCHEMBL27503053 | 0.82 | ACACB (0.48) | ACACBTBXAS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081131-A | Omega-((hetero)alkyl)benz(cd)-indol-2-amines | AMERICAN CYANAMID COMPANY (US) | 1992-01-14 | — | — | US | disclosed |