Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ACACB | O00763 | 5/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.51 |
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657331 | 0.88 | ACACB (0.65) | POLBNPC1RAB9ATBXAS1LMNA | |
| SCHEMBL21591574 | 0.85 | LMNA (0.67) | NPC1RAB9ATBXAS1LMNANAPRT | |
| SCHEMBL10140580 | 0.82 | TBXAS1 (0.49) | POLBTBXAS1LMNANAPRTFDPS | |
| SCHEMBL24609344 | 0.81 | NPC1 (0.79) | NPC1RAB9ALMNA | |
| SCHEMBL2543698 | 0.81 | NPC1 (0.79) | NPC1RAB9ALMNA | |
| SCHEMBL30336917 | 0.80 | CYP3A4 (0.53) | POLBNPC1RAB9AACACB | |
| SCHEMBL2679135 | 0.80 | LMNA (0.55) | LMNAL3MBTL1 | |
| SCHEMBL22022735 | 0.80 | NPC1 (0.56) | NPC1RAB9ALMNAACACB | |
| Carbamic Acid SCHEMBL16857390 | 0.80 | NPC1 (0.71) | NPC1RAB9ALMNA | |
| Carbamic Acid SCHEMBL16857264 | 0.80 | NPC1 (0.71) | NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3636807-A1 | CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 2020-04-15 | — | — | EP | disclosed |