Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | SELE | P16581 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657030 | 0.85 | MAPT (0.49) | ALDH1A1MAPTHPGDRAB9AMAOB | |
| SCHEMBL9655279 | 0.84 | TTR (0.53) | ALDH1A1GAAMAPTHPGDRAB9A | |
| SCHEMBL9658204 | 0.82 | CREBBP (0.46) | ALDH1A1GAAMAPTMAOBHDAC1 | |
| SCHEMBL3366867 | 0.81 | ALDH1A1 (0.55) | ALDH1A1GAAMAPTHPGDRAB9A | |
| SCHEMBL9657506 | 0.81 | PARP10 (0.50) | ALDH1A1GAAMAPTHPGDMAOB | |
| SCHEMBL9656925 | 0.80 | CREBBP (0.43) | ALDH1A1GAAHPGDCREBBP | |
| SCHEMBL3138940 | 0.78 | HPGD (0.79) | ALDH1A1GAAMAPTHPGDRAB9A | |
| SCHEMBL9658219 | 0.77 | HSPB1 (0.53) | ALDH1A1GAAMAPTHPGDRAB9A | |
| SCHEMBL21186228 | 0.77 | NR4A1 (0.50) | ALDH1A1GAAMAPTHPGDBRAF | |
| SCHEMBL9657052 | 0.76 | SMN1; SMN2 (0.50) | ALDH1A1RAB9ACREBBPSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273369-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-04 | — | — | EP | disclosed |
| US-4866091-A | ANTINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |