Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | ECE1 | P42892 | 1/20 | 0.30 |
| ▸ | PGK1 | P00558 | 2/20 | 0.30 |
| ▸ | PGK2 | P07205 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12862664 | 0.75 | GRM5 (0.32) | KDM4EPOLBGAAALDH1A1MAPT | |
| SCHEMBL4134904 | 0.75 | FDPS (0.41) | FDPSTLR7KDM4ERAB9AGAA | |
| SCHEMBL31664981 | 0.71 | — | — | |
| SCHEMBL14380070 | 0.71 | — | — | |
| SCHEMBL179318 | 0.71 | — | — | |
| SCHEMBL19833119 | 0.69 | SLC6A3 (0.32) | RAB9AGAANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20738694 | 0.67 | — | — | |
| SCHEMBL21216514 | 0.67 | — | — | |
| SCHEMBL7660097 | 0.67 | — | — | |
| SCHEMBL13046072 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258618-B1 | DIPHOSPHONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THOSE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |
| US-4777163-A | BONE DISORDERS, RHEUMATIC DISEASES | BOEHRINGER MANNHEIM GMBH (DE) | 1988-10-11 | — | — | US | disclosed |
| EP-0258618-A2 | Diphosphonic acid derivatives, process for their preparation and medicines containing those compounds | Roche Diagnostics GmbH (DE) | 1988-03-09 | — | — | EP | disclosed |