Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 6/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MERTK | Q12866 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31522185 | 0.86 | HSPB1 (0.70) | HSPB1TDP1ATMMEN1KMT2A | |
| SCHEMBL14570718 | 0.85 | VCAM1 (0.56) | HSPB1TDP1ATMMEN1KMT2A | |
| SCHEMBL693017 | 0.82 | MEN1 (0.56) | HSPB1TDP1ATMMEN1KMT2A | |
| SCHEMBL9658125 | 0.80 | HSPB1 (0.62) | HSPB1TDP1ATMMEN1KMT2A | |
| SCHEMBL9655186 | 0.80 | HSPB1 (0.62) | HSPB1TDP1ATMMEN1KMT2A | |
| SCHEMBL1341961 | 0.79 | HSPB1 (0.75) | HSPB1TDP1ATMGAAL3MBTL1 | |
| SCHEMBL9655130 | 0.79 | HSPB1 (0.57) | HSPB1TDP1ATMMEN1KMT2A | |
| SCHEMBL8812343 | 0.78 | TDP1 (0.62) | HSPB1TDP1ATMMEN1KMT2A | |
| SCHEMBL5112932 | 0.77 | MEN1 (0.48) | TDP1MEN1KMT2AMERTKVCAM1 | |
| SCHEMBL9657035 | 0.76 | HSPB1 (0.58) | HSPB1TDP1ATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273369-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-04 | — | — | EP | disclosed |
| US-4866091-A | ANTINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0273369-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-06 | — | — | EP | disclosed |