Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11923449 | 0.81 | ATM (0.63) | ATMKMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL20112842 | 0.80 | KMT2A (0.61) | ATMKMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL21015227 | 0.79 | ATM (0.65) | ATMKMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL25867748 | 0.78 | ATM (0.63) | ATMKMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL19574270 | 0.76 | L3MBTL1 (0.50) | ATMKMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL21015910 | 0.76 | L3MBTL1 (0.65) | ATMKMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL13202812 | 0.75 | L3MBTL1 (0.62) | ATMKMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL19574089 | 0.74 | ATM (0.95) | ATMKMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL28366947 | 0.74 | ATM (0.85) | ATMKMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL10722542 | 0.74 | ATM (0.85) | ATMKMT2AMEN1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0515420-A1 | NITRIC ACID ESTERS OF CYCLOHEXANOL DERIVATIVES. | BOEHRINGER MANNHEIM GMBH (DE) | 1992-12-02 | — | — | EP | disclosed |
| WO-1991012230-A1 | NITRIC ACID ESTERS OF CYCLOHEXANOL DERIVATIVES | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-22 | — | — | WO | disclosed |