Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19176978 | 0.84 | L3MBTL1 (0.48) | KMT2AMEN1L3MBTL1TDP1ATM | |
| SCHEMBL11923449 | 0.84 | ATM (0.63) | KMT2AMEN1L3MBTL1TDP1ATM | |
| SCHEMBL21015227 | 0.82 | ATM (0.65) | KMT2AMEN1L3MBTL1TDP1ATM | |
| SCHEMBL25867748 | 0.80 | ATM (0.63) | KMT2AMEN1L3MBTL1TDP1ATM | |
| SCHEMBL9657504 | 0.80 | ATM (0.53) | KMT2AMEN1L3MBTL1TDP1ATM | |
| SCHEMBL21015910 | 0.79 | L3MBTL1 (0.65) | KMT2AMEN1L3MBTL1TDP1ATM | |
| SCHEMBL12335991 | 0.78 | L3MBTL1 (0.48) | KMT2AMEN1L3MBTL1TDP1ATM | |
| SCHEMBL10534153 | 0.77 | L3MBTL1 (0.88) | KMT2AMEN1L3MBTL1TDP1ATM | |
| SCHEMBL7837034 | 0.77 | L3MBTL1 (0.88) | KMT2AMEN1L3MBTL1TDP1ATM | |
| SCHEMBL150076 | 0.77 | L3MBTL1 (0.88) | KMT2AMEN1L3MBTL1TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118754-A1 | COMPOUNDS | RESPIVERT LTD. (GB) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118754-A1 | COMPOUNDS | LTC4S, CYP11B2, LTB4R2 | KMT2A 3691/4885MEN1 1550/4885L3MBTL1 4133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.