Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27769181 | 0.79 | SLC1A1 (0.35) | SLC1A3SLC1A2SLC1A1DPP4DPP8 | |
| SCHEMBL8650929 | 0.77 | ALOX15 (0.42) | SLC1A3SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL28323716 | 0.77 | SLC1A1 (0.34) | SLC1A3SLC1A2SLC1A1DPP4DPP8 | |
| SCHEMBL3881021 | 0.76 | — | — | |
| SCHEMBL28115491 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL28051624 | 0.74 | — | — | |
| SCHEMBL2458466 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL27725101 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL29047542 | 0.72 | HCAR2 (0.34) | SLC1A3SLC1A2SLC1A1DPP4DPP8 | |
| SCHEMBL14973942 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007562-A1 | CONTROLLING GLUTAMINE/GLUTAMATE RELATED NEURONAL INJURY | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1992-05-14 | — | — | WO | claimed |
| US-5158976-A | CONTROLLING GLUTAMINE/GLUTAMATE RELATED NEURONAL INJURY | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1992-10-27 | — | — | US | disclosed |
| WO-1992007562-A1 | CONTROLLING GLUTAMINE/GLUTAMATE RELATED NEURONAL INJURY | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1992-05-14 | — | — | WO | disclosed |