Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15373370 | 0.84 | ALOX15 (0.41) | ALOX15ALDH1A1NPSR1GLO1LMNA | |
| SCHEMBL27940805 | 0.83 | ALOX15 (0.39) | ALOX15ALDH1A1NPSR1GLO1LMNA | |
| SCHEMBL27940803 | 0.83 | ALOX15 (0.39) | ALOX15ALDH1A1NPSR1GLO1LMNA | |
| Hydrochloric Acid SCHEMBL29047542 | 0.81 | HCAR2 (0.34) | ALDH1A1LMNATSHRGAASLC1A3 | |
| SCHEMBL27769181 | 0.79 | SLC1A1 (0.35) | ALDH1A1TSHREGLN1SLC1A3SLC1A2 | |
| SCHEMBL3294728 | 0.78 | ALDH1A1 (0.44) | ALOX15ALDH1A1NPSR1GLO1LMNA | |
| SCHEMBL12069016 | 0.78 | — | — | |
| SCHEMBL2231963 | 0.78 | — | — | |
| SCHEMBL3188321 | 0.78 | — | — | |
| SCHEMBL9657602 | 0.77 | SLC1A3 (0.34) | SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672648-B1 | Threo (2R,3S)-3-amino-2-hydroxypentanoic acid and threo (2R,3S)-3-(p-methoxy-benzyloxycarbonyl/FMOC) amino-2-hydroxy-pentanoic acid | ZAIDAN HOJIN BISEIBUTSU (JP) | 1998-09-23 | — | — | EP | disclosed |
| EP-0672648-A1 | Threo-3-amino-2-hydroxypentanoic acid and threo (2R,3S), (2S,3R)-3-(p-methoxy-benzyloxycarbonyl) amino-2-hydroxy-pentanoic acid | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1995-09-20 | — | — | EP | disclosed |
| US-5359138-A | Endopeptidase inhibitors for treatment of amnesia and autoimmune diseases | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1994-10-25 | — | — | US | disclosed |
| US-5162500-A | POSTSTATIN AND RELATED COMPOUNDS OR SALTS THEREOF | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0423358-A1 | POSTOSTATIN AND RELATED COMPOUND THEREOF, OR THEIR SALTS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1991-04-24 | — | — | EP | disclosed |