Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NQO1 | P15559 | 3/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.40 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9654941 | 0.86 | MAPT (0.47) | MAPTALDH1A1HSD17B10TSHRMAPK1 | |
| SCHEMBL9449015 | 0.83 | MAPT (0.45) | MAPTALDH1A1HSD17B10TSHRNQO1 | |
| SCHEMBL6273226 | 0.81 | ALDH1A1 (0.50) | MAPTALDH1A1HSD17B10TSHRMAPK1 | |
| SCHEMBL9657047 | 0.81 | ALDH1A1 (0.47) | MAPTALDH1A1HSD17B10TSHRMAPK1 | |
| SCHEMBL9657675 | 0.80 | NQO1 (0.44) | MAPTALDH1A1HSD17B10TSHRNQO1 | |
| SCHEMBL9657735 | 0.77 | TSHR (0.43) | MAPTALDH1A1HSD17B10TSHRMAPK1 | |
| SCHEMBL8489307 | 0.76 | NQO1 (0.65) | MAPTALDH1A1HSD17B10NQO1MEN1 | |
| SCHEMBL8838773 | 0.76 | MAPT (0.52) | MAPTALDH1A1HSD17B10TSHRMEN1 | |
| SCHEMBL9448851 | 0.75 | GAA (0.41) | MAPTALDH1A1TSHRNQO1MEN1 | |
| SCHEMBL11064590 | 0.75 | MAPT (0.50) | MAPTALDH1A1HSD17B10MAPK1NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |