Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.43 |
| ▸ | TUBB | P07437 | 3/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657047 | 0.91 | ALDH1A1 (0.47) | MAPTALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL9657865 | 0.86 | MAPT (0.41) | MAPTALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL9449015 | 0.83 | MAPT (0.45) | MAPTALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL11064590 | 0.82 | MAPT (0.50) | MAPTALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL9627800 | 0.79 | ABCB11 (0.43) | MAPTALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL9656740 | 0.79 | MAPT (0.48) | MAPTALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL9657675 | 0.77 | NQO1 (0.44) | MAPTALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL9628139 | 0.76 | ABCB11 (0.46) | MAPTALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL2022420 | 0.73 | MAPT (0.49) | MAPTALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL2023572 | 0.73 | MAPT (0.49) | MAPTALDH1A1HSD17B10KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |