Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9658140 | 1.00 | IMPDH2 (0.35) | IMPDH2ALOX15MEN1CYP3A4KMT2A | |
| SCHEMBL9658145 | 1.00 | IMPDH2 (0.35) | IMPDH2ALOX15MEN1CYP3A4KMT2A | |
| SCHEMBL9658122 | 0.83 | ALOX15 (0.34) | IMPDH2ALOX15 | |
| SCHEMBL9660324 | 0.80 | IMPDH2 (0.38) | IMPDH2 | |
| SCHEMBL9660346 | 0.79 | IMPDH2 (0.35) | IMPDH2 | |
| SCHEMBL9660025 | 0.78 | IMPDH2 (0.34) | IMPDH2 | |
| SCHEMBL9658119 | 0.78 | MAOB (0.40) | — | |
| SCHEMBL9660014 | 0.78 | MAOB (0.40) | — | |
| SCHEMBL10438624 | 0.74 | IMPDH2 (0.42) | IMPDH2CYP3A4IMPDH1 | |
| SCHEMBL10916603 | 0.73 | IMPDH2 (0.33) | IMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110955-A | Chiral rhodium or palladium-diphosphine catalyst | HOFFMANN-LA ROCHE INC. (US) | 1992-05-05 | — | — | US | disclosed |
| EP-0392389-A2 | Process for the preparation of vinyl compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1990-10-17 | — | — | EP | disclosed |