Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.60 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.52 |
| ▸ | CD74 | P04233 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309405 | 0.79 | HSP90AB1 (0.68) | HRH4HRH3KCNMA1 | |
| SCHEMBL12022159 | 0.77 | KCNMA1 (0.69) | HRH4KCNMA1CD74MIFCYP19A1 | |
| SCHEMBL4327556 | 0.76 | KCNMA1 (0.63) | HRH4HRH3KCNMA1CD74MIF | |
| SCHEMBL23071440 | 0.75 | HRH4 (0.51) | HRH4HRH3KCNMA1CD74MIF | |
| SCHEMBL5287307 | 0.74 | HDAC8 (0.61) | CYP19A1 | |
| SCHEMBL27777026 | 0.73 | GBA1 (0.57) | HRH4HRH3CYP19A1GBA1NPC1 | |
| SCHEMBL18465489 | 0.72 | GBA1 (0.53) | HRH4HRH3CYP19A1GBA1 | |
| SCHEMBL12990471 | 0.72 | KCNMA1 (0.55) | HRH4HRH3KCNMA1CD74MIF | |
| SCHEMBL26254271 | 0.72 | KCNMA1 (0.55) | HRH4HRH3KCNMA1CD74MIF | |
| SCHEMBL16023626 | 0.72 | ALDH1A1 (0.48) | HRH4HRH3CYP19A1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081131-A | Omega-((hetero)alkyl)benz(cd)-indol-2-amines | AMERICAN CYANAMID COMPANY (US) | 1992-01-14 | — | — | US | disclosed |