Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655283 | 0.82 | HSPB1 (0.57) | HSPB1L3MBTL1SMN1; SMN2LMNAPOLB | |
| SCHEMBL9658316 | 0.82 | HSPB1 (0.57) | HSPB1L3MBTL1MAPTALDH1A1KMT2A | |
| SCHEMBL9657033 | 0.82 | HSPB1 (0.56) | HSPB1L3MBTL1MAPTALDH1A1KMT2A | |
| SCHEMBL10960022 | 0.78 | HSPB1 (0.68) | HSPB1L3MBTL1MAPTKMT2AMEN1 | |
| SCHEMBL9655263 | 0.78 | HSPB1 (0.51) | HSPB1MAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL10956911 | 0.75 | HSPB1 (0.63) | HSPB1L3MBTL1MAPTKMT2ALMNA | |
| SCHEMBL9658338 | 0.75 | HSPB1 (0.46) | HSPB1L3MBTL1MAPTALDH1A1FBP1 | |
| SCHEMBL8136193 | 0.73 | RECQL (0.44) | L3MBTL1MAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL9416413 | 0.73 | CES2 (0.50) | L3MBTL1MAPTALDH1A1KMT2ALMNA | |
| SCHEMBL9655201 | 0.73 | HSPB1 (0.53) | HSPB1L3MBTL1MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273369-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-04 | — | — | EP | disclosed |
| US-4866091-A | ANTINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0273369-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-06 | — | — | EP | disclosed |