SCHEMBL9658666

SCHEMBL9658666

CCCn1c(-c2ccccc2)c(C(c2ccccc2)c2c(-c3ccccc3)n(CCC)c3ccccc23)c2ccccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 4/20 0.43
POLB P06746 3/20 0.43
LMNA P02545 2/20 0.43
USP2 O75604 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 8/20 0.43
HPGD P15428 4/20 0.43
FNTA P49354 1/20 0.42
FNTB P49356 1/20 0.42
PDE5A O76074 1/20 0.42
PGR P06401 1/20 0.42
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9658006 0.80 ALDH1A1 (0.51) GAAMAPTLMNAALDH1A1HPGD
SCHEMBL9657054 0.78 GRIK2 (0.49) KDM4EMAPTPOLBLMNAMAPK1
SCHEMBL4785184 0.76 KDM4E (0.51) KDM4EGAAMAPTPOLBLMNA
SCHEMBL9658044 0.74 RORA (0.49) KDM4ELMNATDP1ALDH1A1HPGD
SCHEMBL7454319 0.73 CYP19A1 (0.48) KDM4EMAPTPOLBLMNAUSP2
SCHEMBL30587346 0.73 CYP19A1 (0.48) KDM4EMAPTPOLBLMNAUSP2
SCHEMBL5259155 0.72 ALDH1A1 (0.50) KDM4EMAPTPOLBUSP2TSHR
SCHEMBL9657072 0.72 CNR2 (0.52) KDM4EMAPT
SCHEMBL10663044 0.71 GRIK2 (0.55) KDM4EGAAMAPTPOLBLMNA
SCHEMBL153959 0.70 ALDH1A1 (0.62) KDM4EGAAMAPTPOLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5130291-A HEAT-SENSITIVE RECORDING PAPER OSAKA SEALING PRINTING CO., LTD. (JP) 1992-07-14 US disclosed
EP-0133182-B1 OXIDATION-REDUCTION COLOR PRODUCTION-TYPE HEAT-SENSITIVE RECORDING UNIT MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-03-15 EP disclosed
EP-0055847-B1 PRESSURE SENSITIVE RECORDING UNIT MITSUI TOATSU CHEMICALS, Inc. (JP) 1986-04-02 EP disclosed
US-4561000-A METHINE-TYPE CHROMOGEN, BENZOQUINONE OXIDIZER, COLOR PRODUCTION SENSITIVITY REGULATOR, SUBSTRATE MITSUI TOATSU CHEMICALS, INC. (JP) 1985-12-24 US disclosed
EP-0133182-A1 OXIDATION-REDUCTION COLOR PRODUCTION-TYPE HEAT-SENSITIVE RECORDING UNIT MITSUI TOATSU CHEMICALS, Inc. (JP) 1985-02-20 EP disclosed
US-4398753-A METHINE-TYPE DYES AND QUINONE DERIVATIVE IN REDOX SYSTEM FOR CARBON-FREE REPRODUCTION MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1983-08-16 US disclosed
EP-0055847-A1 Pressure sensitive recording unit MITSUI TOATSU CHEMICALS, Inc. (JP) 1982-07-14 EP disclosed