Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | PEPD | P12955 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21340469 | 0.92 | LTA4H (0.40) | LTA4HPEPDFKBP1ANR1I2IDO1 | |
| SCHEMBL9803063 | 0.85 | ACE (0.40) | LTA4HPEPDMAPTCA2F2 | |
| SCHEMBL9803068 | 0.85 | ACE (0.40) | LTA4HPEPDMAPTCA2F2 | |
| SCHEMBL15434618 | 0.79 | NR1I2 (0.54) | LTA4HFKBP1ANR1I2POLBMAPT | |
| SCHEMBL14115082 | 0.79 | NR1I2 (0.54) | LTA4HFKBP1ANR1I2POLBMAPT | |
| SCHEMBL29020295 | 0.77 | NR1I2 (0.50) | LTA4HFKBP1ANR1I2POLBCYP3A4 | |
| SCHEMBL12156508 | 0.77 | LTA4H (0.44) | LTA4HPEPDFKBP1AIDO1POLB | |
| SCHEMBL9659299 | 0.76 | NR1I2 (0.49) | LTA4HFKBP1ANR1I2POLBCYP3A4 | |
| SCHEMBL15920930 | 0.76 | NR1I2 (0.49) | LTA4HFKBP1ANR1I2POLBCYP3A4 | |
| SCHEMBL18831801 | 0.76 | NR1I2 (0.49) | LTA4HFKBP1ANR1I2POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309624-B1 | COMPOSITION FOR ENHANCING PERCUTANEOUS ADMINISTRATION OF MEDICINE | NITTO DENKO CORPORATION (JP) | 1992-03-11 | — | — | EP | disclosed |
| EP-0309624-A1 | Composition for enhancing percutaneous administration of medicine | NITTO DENKO CORPORATION (JP) | 1989-04-05 | — | — | EP | disclosed |