Sugi Predict

Sugi Predict / Compounds / SCHEMBL21340469

SCHEMBL21340469

SCHEMBL21340469

CCCC(CC)CN1CCCC1C(=O)OC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LTA4H P09960 2/20 0.40
▸ PEPD P12955 2/20 0.39
▸ FKBP1A P62942 2/20 0.39
▸ IDO1 P14902 1/20 0.38
▸ POLB P06746 1/20 0.37
▸ F2 P00734 1/20 0.36
▸ ADRA1D P25100 1/20 0.35
▸ ADRA1A P35348 1/20 0.35
▸ ADRA1B P35368 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.35
▸ XPNPEP1 Q9NQW7 1/20 0.34
▸ GAA P10253 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ CYP3A4 P08684 2/20 0.33
▸ MAPT P10636 2/20 0.33
▸ NR1I2 O75469 1/20 0.33
▸ SLC6A2 P23975 1/20 0.33
▸ SLC6A4 P31645 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9658671 0.92 LTA4H (0.38) LTA4HPEPDFKBP1AIDO1POLB
SCHEMBL12156508 0.79 LTA4H (0.44) LTA4HPEPDFKBP1AIDO1POLB
SCHEMBL18482504 0.77 FKBP1A (0.51) LTA4HPEPDFKBP1APOLBADRA1D
SCHEMBL9649182 0.77 FKBP1A (0.51) LTA4HPEPDFKBP1APOLBADRA1D
SCHEMBL10182480 0.77 FKBP1A (0.51) LTA4HPEPDFKBP1APOLBADRA1D
SCHEMBL8977442 0.77 LTA4H (0.47) LTA4HPEPDFKBP1APOLBADRA1D
SCHEMBL3315632 0.77 LTA4H (0.47) LTA4HPEPDFKBP1APOLBADRA1D
SCHEMBL12677313 0.77 LTA4H (0.47) LTA4HPEPDFKBP1APOLBADRA1D
SCHEMBL9803063 0.76 ACE (0.40) LTA4HPEPDF2L3MBTL1MAPT
SCHEMBL9803068 0.76 ACE (0.40) LTA4HPEPDF2L3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10640484-B2 Method for producing (R)-5-(3,4-difluorophenyl)-5-[(3-methyl-2-oxopyridin-1(2H)-yl)methyl]imidazolidine-2,4-dione and intermediate for producing same KAKEN PHARMACEUTICAL CO., LTD. (JP) 2020-05-05 — — US disclosed
US-20190276428-A1 METHOD FOR PRODUCING (R)-5-(3,4-DIFLUOROPHENYL)-5-[(3-METHYL-2-OXOPYRIDIN-1(2H)-YL)METHYL]IMIDAZOLIDINE-2,4-DIONE AND INTERMEDIATE FOR PRODUCING SAME KAKEN PHARMACEUTICAL CO., LTD. (JP) 2019-09-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190276428-A1 METHOD FOR PRODUCING (R)-5-(3,4-DIFLUOROPHENYL)-5-[(3-METHYL-2-OXOPYRIDIN-1(2H)-YL)METHYL]IMIDAZOLIDINE-2,4-DIONE AND INTERMEDIATE FOR PRODUCING SAME DHPS, MRM1, PRMT5 LTA4H 2119/4885PEPD 3996/4885FKBP1A 2486/4885
US-10640484-B2 Method for producing (R)-5-(3,4-difluorophenyl)-5-[(3-methyl-2-oxopyridin-1(2H)-yl)methyl]imidazolidine-2,4-dione and intermediate for producing same DHPS, MRM1, PRMT5 LTA4H 2119/4885PEPD 3996/4885FKBP1A 2486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.