SCHEMBL9658673

SCHEMBL9658673

CCCCCC[C@@]1(C(=O)OC)CCCN1CC

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.40
CYP4A11 Q02928 1/20 0.40
POLA1 P09884 2/20 0.35
EPHX1 P07099 1/20 0.33
NAAA Q02083 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
KDM4E B2RXH2 1/20 0.32
DNTT P04053 1/20 0.32
POLB P06746 1/20 0.32
OPRL1 P41146 1/20 0.31
DPP4 P27487 1/20 0.31
FAP Q12884 1/20 0.31
DPP7 Q9UHL4 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9803074 0.84 L3MBTL1 (0.34) L3MBTL1OPRL1MEN1KMT2ATDP1
SCHEMBL11660321 0.77 CYP4F2 (0.41) CYP4F2CYP4A11POLA1EPHX1NAAA
SCHEMBL28110693 0.74 CPB2 (0.36) L3MBTL1
SCHEMBL415319 0.73 CYP4F2 (0.33) CYP4F2CYP4A11DPP4FAPDPP7
SCHEMBL11664039 0.71 CYP4F2 (0.37) CYP4F2CYP4A11POLA1EPHX1DNTT
SCHEMBL441356 0.70 GRIN2B (0.35) CYP4F2CYP4A11EPHX1L3MBTL1MEN1
SCHEMBL25347423 0.70 NPSR1 (0.35) CYP4F2CYP4A11DPP4MEN1KMT2A
SCHEMBL11662231 0.70 CYP4F2 (0.37) CYP4F2CYP4A11POLA1EPHX1
SCHEMBL25347426 0.70 NPSR1 (0.35) CYP4F2CYP4A11DPP4MEN1KMT2A
SCHEMBL3382769 0.70 CPB2 (0.35) L3MBTL1KDM4EOPRL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0309624-B1 COMPOSITION FOR ENHANCING PERCUTANEOUS ADMINISTRATION OF MEDICINE NITTO DENKO CORPORATION (JP) 1992-03-11 EP disclosed
EP-0309624-A1 Composition for enhancing percutaneous administration of medicine NITTO DENKO CORPORATION (JP) 1989-04-05 EP disclosed