Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19835254 | 1.00 | HTT (0.43) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL19835199 | 1.00 | HTT (0.43) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL19834961 | 0.85 | LPAR3 (0.44) | — | |
| SCHEMBL2900302 | 0.84 | MEN1 (0.52) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL7286646 | 0.83 | MEN1 (0.41) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL7286622 | 0.83 | CES2 (0.31) | CES2 | |
| SCHEMBL7285766 | 0.83 | S1PR2 (0.40) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL7351088 | 0.83 | MEN1 (0.50) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL23696250 | 0.83 | MEN1 (0.48) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL20017922 | 0.83 | HTT (0.48) | HTTTHRBMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200078272-A1 | METHOD FOR PRODUCING CERAMIDE MICROPARTICLE DISPERSION | KAO CORPORATION (JP) | 2020-03-12 | — | — | US | disclosed |
| EP-3536399-A1 | METHOD FOR PRODUCING CERAMIDE MICROPARTICLE DISPERSION | Kao Corporation (JP) | 2019-09-11 | — | — | EP | disclosed |
| EP-3275448-A1 | NUCLEIC ACID-CONTAINING LIPID NANOPARTICLES | Kyowa Hakko Kirin Co., Ltd. (JP) | 2018-01-31 | — | — | EP | disclosed |
| EP-0466211-A1 | Antistatic multiply films | W.R. Grace & Co.-Conn. (US) | 1992-01-15 | — | — | EP | disclosed |
| US-5025922-A | Aromatic sulfonamide | W. R. GRACE & CO.-CONN. (US) | 1991-06-25 | — | — | US | disclosed |
| US-5024792-A | Mixing hydrophilic copolymer with stable hydrophobic aromatic sulfonamides | W. R. GRACE & CO.-CONN. (US) | 1991-06-18 | — | — | US | disclosed |
| US-5001015-A | Antistatic polyolefin compositions and antistatic polyolefin films made therefrom, including oriented films | W. R. GRACE & CO.-CONN. (US) | 1991-03-19 | — | — | US | disclosed |
| US-4899521-A | AROMATIC SULFONAMIDE | W. R. GRACE & CO. - CONN. (US) | 1990-02-13 | — | — | US | disclosed |
| US-4898771-A | Agent for imparting antistatic characteristics to a thermoplastic polymer and a thermoplastic polymer composition containing the agent | W. R. GRACE & CO.-CONN. (US) | 1990-02-06 | — | — | US | disclosed |
| US-4882894-A | MULTILAYER POLYAMIDES, POLYETHYLENE WITH BENZENESULFONAMIDES | W. R. GRACE & CO.-CONN. (US) | 1989-11-28 | — | — | US | disclosed |
| US-4800115-A | POLYOXYALKYLENE GLYCOLS ETHERIFIED, POLYETHYLENE, MONOGLYCERIDES | W. R. GRACE & CO. (US) | 1989-01-24 | — | — | US | disclosed |
| EP-0264269-A1 | Use of thermoplastic polymer composition film containing an antistatic agent | W.R. Grace & Co.-Conn. (US) | 1988-04-20 | — | — | EP | disclosed |
| EP-0264270-A2 | Thermoplastic polymer composition having antistatic characteristics | W.R. Grace & Co.-Conn. (US) | 1988-04-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200078272-A1 | METHOD FOR PRODUCING CERAMIDE MICROPARTICLE DISPERSION | SGMS1, CERS2, SGMS2 | HTT 4433/4885THRB 4859/4885MEN1 903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.