Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660462 | 0.80 | HPGD (0.39) | GLAPOLBHPGDKMT2AMEN1 | |
| SCHEMBL9661603 | 0.74 | NPC1 (0.50) | POLBHPGDKMT2ANPC1RAB9A | |
| SCHEMBL9658772 | 0.72 | POLB (0.70) | POLBHPGDKMT2AMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL11749763 | 0.71 | POLB (0.68) | POLBHPGDKMT2AMEN1NPC1 | |
| SCHEMBL9660166 | 0.69 | NPC1 (0.36) | POLBHPGDKMT2AMEN1NPC1 | |
| SCHEMBL9660169 | 0.69 | NPC1 (0.36) | POLBHPGDKMT2AMEN1NPC1 | |
| SCHEMBL9658792 | 0.69 | ALDH1A1 (0.44) | NPC1RAB9AALDH1A1ALOX15CASP1 | |
| SCHEMBL9660740 | 0.69 | NPC1 (0.41) | POLBHPGDKMT2AMEN1NPC1 | |
| SCHEMBL9690711 | 0.69 | POLB (0.41) | POLBHPGDKMT2AMEN1NPC1 | |
| SCHEMBL9660186 | 0.69 | NPC1 (0.41) | POLBHPGDKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520274-A2 | 2-(-4-substituted-phenylhydrazino)-2-thiazoline and 2-(-4-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |