Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11749763 | 0.98 | POLB (0.68) | POLBSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL7354403 | 0.82 | POLB (1.00) | POLBSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL9690709 | 0.80 | POLB (0.50) | POLBSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL9690723 | 0.80 | POLB (0.50) | POLBSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL9581167 | 0.80 | ALDH1A1 (0.55) | POLBSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL9690774 | 0.76 | POLB (0.46) | POLBSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL9690695 | 0.76 | RAB9A (0.57) | POLBSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL9689564 | 0.76 | LMNA (0.48) | POLBSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL9690030 | 0.76 | NPC1 (0.47) | POLBSMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL11750587 | 0.75 | MAPK1 (0.49) | POLBSMN1; SMN2NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520275-A2 | 2-(3-Substituted phenylhydrazino)-2-thiazoline and 2-(3-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |
| EP-0520274-A2 | 2-(-4-substituted-phenylhydrazino)-2-thiazoline and 2-(-4-substituted phenylazo)-2-thiazoline, their preparation and their use against ectoparasites | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |
| US-4575501-A | 2-Arylhydrazino-2-thiazolines, acyl derivatives of these compounds, 2-arylazo-2-thiazolines, preparation processes, and their use for combating ectoparasites and endoparasites | BAYER AKTIENGESELLSCHAFT (DE) | 1986-03-11 | — | — | US | disclosed |
| EP-0073393-A1 | 2-Arylhydrazino-2-thiazolines, acyl derivatives of the same, 2-arylazo-2-thiazolines, process for their preparation and their use in the control of ectoparasites and endoparasites | BAYER AG (DE) | 1983-03-09 | — | — | EP | disclosed |
| US-4046753-A | ANTHELMINTICS, HYPOTENSIVE | MERCK & CO., INC. (US) | 1977-09-06 | — | — | US | disclosed |