Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8025733 | 0.78 | RARB (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5431954 | 0.77 | RARB (0.55) | RARBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4598744 | 0.75 | GABRP (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL600023 | 0.72 | HMGB1 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6056231 | 0.72 | TYR (0.41) | RARBALDH1A1HSD17B10KDM4ELMNA | |
| SCHEMBL28428779 | 0.72 | CNR2 (0.43) | RARBALDH1A1PPARA | |
| SCHEMBL27471842 | 0.71 | LMNA (0.47) | ALDH1A1HSD17B10MAPTKDM4EMEN1 | |
| SCHEMBL2697153 | 0.71 | HTT (0.37) | RARBALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL30945773 | 0.71 | HPGD (0.48) | ALDH1A1HPGDHSD17B10HTTCYP1A2 | |
| SCHEMBL983815 | 0.71 | HPGD (0.48) | ALDH1A1HPGDHSD17B10HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089608-A | Preparing cyclic adduct by reacting a di(hydrocarbyl)tin oxide with a dihydric alcohol, alkanolamine, or an enolizable alpha-hydroxy ketone | MCNEIL-PPC, INC. (US) | 1992-02-18 | — | — | US | disclosed |