Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9661167 | 0.90 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1TDP1GLAHTT | |
| SCHEMBL9659058 | 0.88 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1TDP1POLBMAPT | |
| SCHEMBL9661030 | 0.79 | KDM4E (0.51) | SMN1; SMN2ALDH1A1GLAHTTPOLB | |
| SCHEMBL9660800 | 0.79 | CYP46A1 (0.44) | SMN1; SMN2ALDH1A1TDP1GLAHTT | |
| SCHEMBL9658942 | 0.79 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1TDP1GLAHTT | |
| SCHEMBL9661104 | 0.78 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1TDP1GLAHTT | |
| SCHEMBL9660294 | 0.78 | ABL1 (0.53) | SMN1; SMN2ALDH1A1TDP1POLBMAPT | |
| SCHEMBL1403472 | 0.77 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1TDP1HTTPOLB | |
| SCHEMBL30203403 | 0.77 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1TDP1HTTPOLB | |
| SCHEMBL16961496 | 0.76 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1TDP1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118680-A | COMBATING ENDOPARASITES WITH 3-HYDROXYBENZOTHIOPHENES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |