Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660826 | 0.88 | ABL1 (0.49) | ABL1NR4A2SLC6A4SLC6A3RXFP1 | |
| SCHEMBL9661030 | 0.84 | KDM4E (0.51) | MAPTSMN1; SMN2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL9660800 | 0.84 | CYP46A1 (0.44) | NR4A2MAPTSMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL4071201 | 0.83 | ABL1 (0.60) | ABL1NR4A2SLC6A4SLC6A3RXFP1 | |
| SCHEMBL2473934 | 0.79 | ABL1 (0.53) | ABL1NR4A2SLC6A4SLC6A3RXFP1 | |
| SCHEMBL25826611 | 0.78 | ABL1 (0.63) | ABL1NR4A2SLC6A4SLC6A3RXFP1 | |
| SCHEMBL9660328 | 0.78 | POLB (0.58) | SLC6A4SLC6A3MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL9658941 | 0.78 | SMN1; SMN2 (0.46) | MAPTSMN1; SMN2CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL9659040 | 0.77 | CA2 (0.39) | RXFP1MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9660296 | 0.77 | ABL1 (0.53) | ABL1NR4A2RXFP1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118680-A | COMBATING ENDOPARASITES WITH 3-HYDROXYBENZOTHIOPHENES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |