⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346143 | 1.00 | — | — | |
| SCHEMBL20581587 | 0.82 | NAAA (0.37) | — | |
| SCHEMBL20581585 | 0.82 | NAAA (0.37) | — | |
| SCHEMBL23570684 | 0.80 | — | — | |
| SCHEMBL5580598 | 0.80 | — | — | |
| SCHEMBL23570707 | 0.80 | — | — | |
| SCHEMBL21626324 | 0.78 | NAAA (0.33) | — | |
| SCHEMBL7383773 | 0.78 | CCR2 (0.50) | — | |
| SCHEMBL21626323 | 0.78 | NAAA (0.33) | — | |
| SCHEMBL14778920 | 0.78 | CCR2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251143-B1 | 2-Oxo-1-[[(Substituted Sulfonyl)Amino]-Carbonyl]Azetidines | Bristol-Myers Squibb GmbH (DE) | 1992-08-26 | — | — | EP | disclosed |
| US-5106977-A | Intermediates for a process for making 2-oxo-1-[[(substituted sulfonyl)-amino]carbonyl]azetidines | E. R. SQUIBB & SONS, INC. (US) | 1992-04-21 | — | — | US | disclosed |
| US-4980465-A | Process for making 2-oxo-1-[[(substituted sulfonyl)-amino]carbonyl)] azetidines and intermediates used therein | E. R. SQUIBB & SONS, INC. (US) | 1990-12-25 | — | — | US | disclosed |
| US-4889930-A | Process for making 2-oxo-1-((substituted sulfonyl)amino)carbonzyl)azetidines and intermediates used therein | E. R. SQUIBB & SONS, INC. (US) | 1989-12-26 | — | — | US | disclosed |
| EP-0344707-A2 | 2-Oxo-1-[[(substituted sulfonyl)-amino]carbonyl]-azetidine derivatives | E.R. SQUIBB & SONS, INC. (US) | 1989-12-06 | — | — | EP | disclosed |
| US-4871841-A | 2-Oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines | E. R. SQUIBB & SONS, INC. (US) | 1989-10-03 | — | — | US | disclosed |
| EP-0321928-A2 | 2-Oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines | E.R. SQUIBB & SONS, INC. (US) | 1989-06-28 | — | — | EP | disclosed |
| EP-0321844-A2 | Process for making 2-oxo-1-(((substituted sulfonyl)-amino)carbonyl)azetidines and intermediates used therein | E.R. Squibb & Sons, Inc. (US) | 1989-06-28 | — | — | EP | disclosed |
| US-H642-H | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1989-06-06 | — | — | US | disclosed |
| US-4801705-A | 2-oxo-1-(((substituted sulfonyl)amino)-carbonyl)azetidines | E. R. SQUIBB & SONS, INC. (US) | 1989-01-31 | — | — | US | disclosed |
| EP-0085291-B1 | 2-OXO-1-(AMINOCARBONYLAMINOSULFONYLAMINOCARBONYL)AZETIDINES | E.R. Squibb & Sons, Inc. (US) | 1988-08-17 | — | — | EP | disclosed |
| EP-0251143-A1 | 2-Oxo-1-[[(Substituted Sulfonyl)Amino]-Carbonyl]Azetidines | Bristol-Myers Squibb GmbH (DE) | 1988-01-07 | — | — | EP | disclosed |
| US-4670553-A | 2-oxo-1-(aminocarbonylaminosulfonyl-aminocarbonyl)azetidines | E. R. SQUIBB & SONS, INC. (US) | 1987-06-02 | — | — | US | disclosed |
| EP-0062876-B1 | 2-OXO-1-(((SUBSTITUTED SULFONYL)AMINO)CARBONYL)AZETIDINES | E.R. Squibb & Sons, Inc. (US) | 1986-09-24 | — | — | EP | disclosed |
| US-4587047-A | 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines | E. R. SQUIBB & SONS, INC. (US) | 1986-05-06 | — | — | US | disclosed |
| US-4534896-A | 3-Acylamino-2-oxoazetidine-1-(β-oxopropionic acid) | E. R. SQUIBB & SONS, INC. (US) | 1985-08-13 | — | — | US | disclosed |
| US-4529698-A | Culturing Chromobacterium | E. R. SQUIBB & SONS, INC. (US) | 1985-07-16 | — | — | US | disclosed |
| US-4499016-A | 2-Oxo-1-[(acylamino)sulfonyl]azetidines | E. R. SQUIBB & SONS, INC. (US) | 1985-02-12 | — | — | US | disclosed |
| EP-0085291-A1 | 2-Oxo-1-(aminocarbonylaminosulfonylaminocarbonyl)azetidines | E.R. Squibb & Sons, Inc. (US) | 1983-08-10 | — | — | EP | disclosed |
| EP-0062876-A1 | 2-Oxo-1-(((substituted sulfonyl)amino)carbonyl)azetidines | E.R. Squibb & Sons, Inc. (US) | 1982-10-20 | — | — | EP | disclosed |