Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CASP1 | P29466 | 4/20 | 0.36 |
| ▸ | CASP7 | P55210 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
| ▸ | MYLK | Q15746 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9659657 | 0.88 | CLPP (0.39) | CLPPUSP2CYP1A2CASP1CASP7 | |
| SCHEMBL9659792 | 0.84 | CLPP (0.52) | CLPPMEN1KMT2AAKT1MYLK | |
| Hydrochloric Acid SCHEMBL9659901 | 0.81 | MAPT (0.40) | CLPPALDH1A1MEN1KMT2AHTR2A | |
| SCHEMBL9659999 | 0.78 | KCNK3 (0.46) | GPBAR1MAPK1 | |
| Hydrochloric Acid SCHEMBL9658330 | 0.71 | HTR2A (0.52) | HTR2AHTR2CHTR2B | |
| Water SCHEMBL9660223 | 0.71 | HTR2A (0.52) | HTR2AHTR2CHTR2BADORA1ADORA2A | |
| Water SCHEMBL9660219 | 0.71 | HTR2A (0.52) | HTR2AHTR2CHTR2BADORA1ADORA2A | |
| Hydrochloric Acid SCHEMBL9658397 | 0.70 | CYP2C19 (0.45) | CYP1A2ALDH1A1CYP2D6MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9659535 | 0.70 | MAPT (0.40) | CLPPALDH1A1MEN1KMT2AMAPK14 | |
| SCHEMBL9660193 | 0.67 | MAPK1 (0.53) | GPBAR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137890-A | Gastrointestinal disorders, antiulcer agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-08-11 | — | — | US | claimed |
| US-5137890-A | Gastrointestinal disorders, antiulcer agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-08-11 | — | — | US | disclosed |