Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 7/20 | 0.52 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 2/20 | 0.47 |
| ▸ | MYLK | Q15746 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9659657 | 0.89 | CLPP (0.39) | CLPPC5AR1MEN1KMT2AGPBAR1 | |
| SCHEMBL9659722 | 0.84 | CLPP (0.37) | CLPPC5AR1MEN1KMT2AAKT1 | |
| SCHEMBL9659999 | 0.79 | KCNK3 (0.46) | GPBAR1 | |
| SCHEMBL115543 | 0.77 | AKT1 (0.51) | CLPPC5AR1MEN1KMT2AAKT1 | |
| Hydrochloric Acid SCHEMBL9658330 | 0.72 | HTR2A (0.52) | — | |
| Water SCHEMBL9660219 | 0.72 | HTR2A (0.52) | — | |
| Water SCHEMBL9660223 | 0.72 | HTR2A (0.52) | — | |
| SCHEMBL116437 | 0.71 | ALDH1A1 (0.51) | CLPPC5AR1MEN1KMT2AAKT1 | |
| SCHEMBL2341043 | 0.71 | HTR2A (0.57) | CLPPKMT2AACHE | |
| SCHEMBL115542 | 0.71 | LMNA (0.50) | CLPPC5AR1MEN1KMT2AAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137890-A | Gastrointestinal disorders, antiulcer agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1992-08-11 | — | — | US | disclosed |