Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | PLG | P00747 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.53 |
| ▸ | BLM | P54132 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA3 | P07451 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diaminooctane SCHEMBL9175035 | 1.00 | PAOX (0.65) | PAOXLMNAKMT2ATHRBMEN1 | |
| Acetic Acid SCHEMBL7118249 | 1.00 | PAOX (0.65) | PAOXLMNAKMT2ATHRBMEN1 | |
| Acetic Acid SCHEMBL8604919 | 1.00 | PAOX (0.65) | PAOXLMNAKMT2ATHRBMEN1 | |
| Acetic Acid SCHEMBL5382762 | 1.00 | PAOX (0.65) | PAOXLMNAKMT2ATHRBMEN1 | |
| Acetic Acid SCHEMBL6288245 | 1.00 | PAOX (0.65) | PAOXLMNAKMT2ATHRBMEN1 | |
| Diaminooctane SCHEMBL11308186 | 1.00 | PAOX (0.65) | PAOXLMNAKMT2ATHRBMEN1 | |
| Acetic Acid SCHEMBL356900 | 1.00 | PAOX (0.65) | PAOXLMNAKMT2ATHRBMEN1 | |
| Acetic Acid SCHEMBL7122573 | 1.00 | PAOX (0.65) | PAOXLMNAKMT2ATHRBMEN1 | |
| Acetic Acid SCHEMBL11462305 | 0.97 | PAOX (0.62) | PAOXLMNAKMT2ATHRBMEN1 | |
| Putrescine SCHEMBL2761088 | 0.97 | PAOX (0.60) | PAOXLMNAKMT2ATHRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113773490-B | Method for synthesizing polyhexamethylene biguanide from monoguanidine intermediate | 大连百傲化学股份有限公司 | 2023-09-26 | — | — | CN | claimed |
| CN-113773490-A | Method for synthesizing polyhexamethylene biguanide from monoguanidine intermediate | 大连百傲化学股份有限公司 | 2021-12-10 | — | — | CN | claimed |
| EP-4310504-A2 | ACTIVITY-BASED PROBE COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | The Board of Trustees of the Leland Stanford Junior University (US) | 2024-01-24 | — | — | EP | disclosed |
| US-20230391750-A1 | ACTIVITY-BASED PROBE COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-12-07 | — | — | US | disclosed |
| EP-3510380-B1 | ACTIVITY-BASED PROBE COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | UNIV LELAND STANFORD JUNIOR (US) | 2023-11-08 | — | — | EP | disclosed |
| CN-113773490-B | Method for synthesizing polyhexamethylene biguanide from monoguanidine intermediate | 大连百傲化学股份有限公司 | 2023-09-26 | — | — | CN | disclosed |
| EP-4218829-A2 | ACTIVITY-BASED PROBE COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | The Board of Trustees of the Leland Stanford Junior University (US) | 2023-08-02 | — | — | EP | disclosed |
| CN-116217656-A | Activity-based probe compounds, compositions, and methods of use thereof | 里兰斯坦福初级大学理事会 | 2023-06-06 | — | — | CN | disclosed |
| US-11655236-B2 | Activity-based probe compounds, compositions, and methods of use | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-05-23 | — | — | US | disclosed |
| CN-110023740-B | Activity-based probe compounds, compositions, and methods of use thereof | 里兰斯坦福初级大学理事会 | 2023-04-14 | — | — | CN | disclosed |
| EP-2971065-B1 | ACTIVITY-BASED PROBE COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | UNIV LELAND STANFORD JUNIOR (US) | 2022-12-14 | — | — | EP | disclosed |
| US-20080064954-A1 | METHOD OF MEASURING PROPULSION IN LYMPHATIC STRUCTURES | BAYLOR COLLEGE OF MEDICINE (US) | 2008-03-13 | — | — | US | disclosed |
| US-20080056999-A1 | IMAGING AGENTS FOR FUNCTIONAL IMAGING OF LYMPHATIC STRUCTURES | BAYLOR COLLEGE OF MEDICINE (US) | 2008-03-06 | — | — | US | disclosed |
| WO-2008025000-A2 | IMAGING AGENTS FOR FUNCTIONAL IMAGING OF LYMPHATIC STRUCTURES | BAYLOR COLLEGE OF MEDICINE (US) | 2008-02-28 | — | — | WO | disclosed |
| WO-2008025005-A2 | METHOD OF MEASURING PROPULSION IN LYMPHATIC STRUCTURES | BAYLOR COLLEGE OF MEDICINE (US) | 2008-02-28 | — | — | WO | disclosed |
| CN-1256358-C | Binder for abrasive articles, abrasive articles comprising the binder, and methods of making the same | 3M INNOVATIVE PROPERTIES CO (US) | 2006-05-17 | — | — | CN | disclosed |
| WO-2006013596-A1 | SHALE INHIBITORS FOR THE PETROLEUM INDUSTRY | LAMBERTI S.P.A. (IT) | 2006-02-09 | — | — | WO | disclosed |
| CN-1555390-A | Binder for abrasive articles, abrasive articles including the same and method of making same | 3M | 2004-12-15 | — | — | CN | disclosed |
| US-6682574-B2 | CAN BE USED FOR SANDING, GRINDING OR POLISHING VARIOUS SURFACES OF, FOR EXAMPLE, STEEL AND OTHER METALS, WOOD, WOOD-LIKE LAMINATES, PLASTIC, FIBERGLASS, LEATHER OR CERAMICS | 3M INNOVATIVE PROPERTIES COMPANY | 2004-01-27 | — | — | US | disclosed |
| US-5397796-A | Inhibitors of platelet aggregation, metastasis of carcinoma cells and osteoclast binding to the bone surfaces | CASSELLA AG (DE) | 1995-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230391750-A1 | ACTIVITY-BASED PROBE COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | DNPEP, CTSF, CTSE | PAOX 1346/4885LMNA 1508/4885KMT2A 4202/4885 |
| US-11655236-B2 | Activity-based probe compounds, compositions, and methods of use | DNPEP, CTSF, CTSE | PAOX 1346/4885LMNA 1508/4885KMT2A 4202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.